Preparation, Characterization and In-vitro Evaluation of Gamma Oryzanol Loaded Self-nanoemulsifying Drug Delivery Systems
نویسندگان
چکیده
منابع مشابه
Development, Characterization, and Pharmacodynamic Evaluation of Hydrochlorothiazide Loaded Self-Nanoemulsifying Drug Delivery Systems
The objective of the current work was to develop optimized self-nanoemulsifying drug delivery systems (SNEDDS) and evaluate their in vitro and in vivo performance. The research comprised various studies which includes solubility studies in various vehicles, pseudoternary phase diagram construction, and preparation and characterization of SNEDDS along with in vitro dissolution and in vivo pharma...
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Gamma-scintigraphy is applied extensively in the development and evaluation of pharmaceutical delivery systems, particularly for monitoring formulations in the gastrointestinal and respiratory tracts. The radiolabelling is generally achieved by the incorporation of an appropriate radionuclide such as technetium-99m or indium-111 into the formulation or by addition of a non-radioactive iso...
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BACKGROUND Akebia saponin D (ASD) exerts various pharmacological activities but with poor oral bioavailability. In this study, a self-nanoemulsifying drug delivery system (SNEDDS) based on the drug-phospholipid complex technique was developed to improve the oral absorption of ASD. METHODS ASD-phospholipid complex (APC) was prepared using a solvent-evaporation method and characterized by infra...
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ژورنال
عنوان ژورنال: Advances in pharmacology and pharmacy
سال: 2023
ISSN: ['2332-0036', '2332-0044']
DOI: https://doi.org/10.13189/app.2023.110208